Cannabis and the Endocannabinoid System

Background. The medicinal properties of cannabis have been known for a very long period of time. Some of the earliest writings about cannabis came from China over 5000 years ago! The medical use of cannabis was widespread throughout much of the world by the 19th century. It was an integral part of early American medicine [...]

Autoimmune Disorders and Medical Marijuana (Cannabis)

Autoimmune Disorders and Medical Marijuana (Cannabis) Summary: An autoimmune disorder occurs when the immune system becomes overactive and starts producing antibodies to attack our own cells (auto-antibodies). Autoimmune disorders are characterized by inflammation caused by these auto-antibodies. There are 80-100 different autoimmune disorders affecting 24-50 million people in the US. Examples of autoimmune disorders [...]

Depression and Medical Marijuana (Cannabis)

Depression and Medical Marijuana (Cannabis) Summary: Cannabis use is associated with elevated mood and decreased depression in patients with chronic diseases. On the other hand, pure oral THC administration to depressed individuals can also result in dysphoria (a state of unease. The opposite of euphoria) in some patients, especially those who are naïve to the [...]

Ehlers-Danlos Syndrome (EDS) and Medical Marijuana (Cannabis)

Ehlers-Danlos Syndrome (EDS) and Medical Marijuana (Cannabis) Summary: Ehlers-Danlos Syndrome (EDS) is a group of disorders affecting the connective tissues that support the skin, bones, blood vessels, and many other organs. Hallmark symptoms include extremely flexible joints and highly elastic skin which is prone to bruising. These conditions are inheritable and commonly under-diagnosed. It is [...]

Alzheimers Disease, Our Mom and Medical Marijuana (Cannabis)

This story needs to be told with the hope that our journey with Mom will help others going through similar challenges. Background. In her younger years, Mom ("Betty Jo") was one of the smartest people I have ever known. She remembered the words of every song she had ever heard along with the eye color [...]

Coronary Disease/Atherosclerosis and Medical Marijuana (Cannabis)

Coronary Disease/Atherosclerosis and Cannabis Summary. Modulation of the Endocannabinoid System by a non-inhalation route may have a beneficial effect on the development of atherosclerosis. There is concern that smoking cannabis may not have this benefit and may actually precipitate angina in people with coronary disease. https://pubmed.ncbi.nlm.nih.gov/22278660/ Coronary Artery Disease (CAD) is also known as Atherosclerotic [...]

Excitotoxicity and Medical Marijuana (Cannabis)

Excitotoxicity and Medical Marijuana (Cannabis) Summary. In Excitotoxicity, nerve cells suffer damage or death when the levels of otherwise necessary and safe neurotransmitters such as glutamate, AMPA, or NMDA become pathologically high resulting in excessive stimulation of receptors. Glutamate is an excitatory neurotransmitter with an important function in the brain. However, at high levels, Glutamate [...]

Why Don’t More Healthcare Professionals know about the Medicinal Benefits of Medical Marijuana (Cannabis)?

Why Don’t More Healthcare Professionals know about the Medicinal Benefits of Cannabis? I am frequently asked this question so I will try to provide a logical answer! In short, understanding how cannabis works in the body requires a lot of dedication and study. The first written documentation about the medicinal properties of cannabis came from [...]

Neuropathy and Medical Marijuana (Cannabis)

Neuropathy and Cannabis Summary: Peripheral neuropathy is the most common form of neuropathy and Diabetes is the most common cause of peripheral neuropathy. “Neuropathy is one of the most painful, unpleasant, and frustrating conditions, and it affects hundreds of millions of people each year. With unending, frustrating pain and no real solution, neuropathic pain sufferers [...]